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Highest antigen sequence indentity to the following orthologs: Mouse (44%), Rat (44%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84932. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a sperm protein that is associated with the nucleus but, although a role in spermatogenesis is suggested, the specific function of this family member has not yet been determined. Polymorphisms in this gene may be associated with prostate cancer susceptibility. [provided by RefSeq, Apr 2014].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cancer/testis antigen 11.4; cancer/testis antigen family 11, member 4; CT11.4; Nuclear-associated protein SPAN-Xd; nuclear-associated protein SPAN-Xe; SPANX family member D; SPANX family, member D; SPANX family, member E; SPANX-D; Sperm protein associated with the nucleus on the X chromosome D; sperm protein associated with the nucleus, X chromosome, family member D; sperm protein associated with the nucleus, X chromosome, family member E
基因别名: CT11.4; dJ171K16.1; SPANX-C; SPANX-D; SPANX-E; SPANXD; SPANXE
UniProt ID: (Human) Q9BXN6
Entrez Gene ID: (Human) 64648