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Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62352. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hSpc24; Kinetochore protein Spc24; SPC24, NDC80 kinetochore complex component, homolog; spindle pole body component 24 homolog
基因别名: SPBC24; SPC24
UniProt ID: (Human) Q8NBT2
Entrez Gene ID: (Human) 147841