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Highest antigen sequence indentity to the following orthologs: Mouse (28%), Rat (28%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58963. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Involved in the spindle-assembly checkpoint. Required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores. Required for the correct localization of the active form of Aurora B in prometaphase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hSpy/Ringo C; Rapid inducer of G2/M progression in oocytes C; RINGO C; SPDYC; speedy; speedy C; speedy homolog C; Speedy protein C
基因别名: Ringo2; RINGOC; SPDYC
UniProt ID: (Human) Q5MJ68
Entrez Gene ID: (Human) 387778