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Highest antigen sequence indentity to the following orthologs: Mouse (91%), Rat (91%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111699. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. The protein is positioned upstream of RAS activation and impairs the formation of active GTP-RAS.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Protein sprouty homolog 4; Sprouty 4; sprouty homolog 4; Spry-4
基因别名: HH17; SPRY4
UniProt ID: (Human) Q9C004
Entrez Gene ID: (Human) 81848