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产品信息
RP-104223
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
DSDEEDLCISNKWTFQRTSRRWSRVDDLYTLLPRGDRNGSPGGTGMRNTTSSESVLTDLSEPEVCSIHSESSGGSDSRSQPGQCC
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (87%), Rat (87%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63622. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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生物信息学
蛋白别名: 46H23.2; Deleted in liver cancer 2 protein; DLC-2; long intergenic non-protein coding RNA 464; Rho GTPase activating protein on chromosome 13q12; Rho GTPase-activating protein; STA13; StAR-related lipid transfer (START) domain containing 13; StAR-related lipid transfer domain containing 13; StAR-related lipid transfer protein 13; StARD13; START domain-containing protein 13
基因别名: ARHGAP37; DLC2; GT650; LINC00464; STARD13
UniProt ID: (Human) Q9Y3M8
Entrez Gene ID: (Human) 90627
