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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56181. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 7-Sep; CDC10 (cell division cycle 10, S. cerevisiae, homolog); CDC10 protein homolog; septin 7 variant 4; Septin-7
基因别名: CDC10; CDC3; NBLA02942; SEPT7; SEPT7A; SEPTIN7
UniProt ID: (Human) Q16181
Entrez Gene ID: (Human) 989