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Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52709. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
May be involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain or may serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis. Plays a role in dendrite formation by melanocytes (PubMed:23999003).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Synaptotagmin IV; Synaptotagmin-4; Synaptotagmin4; SytIV
基因别名: HsT1192; KIAA1342; SYT4
UniProt ID: (Human) Q9H2B2
Entrez Gene ID: (Human) 6860