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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-64090. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C20orf100; GCX1; Glutaminase-interacting protein 3; Tax interaction protein 1; Tax-interacting protein 1; Tax1 (human T-cell leukemia virus type I) binding protein 3; Tax1-binding protein 3; TAX1BP3; TIP-1
基因别名: TAX1BP3; TIP-1; TIP1
UniProt ID: (Human) O14907
Entrez Gene ID: (Human) 30851