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This peptide corresponds to 22 amino acids near the carboxy terminus of human TBC1D1.
PEP-0506 can be used as a blocking peptide with polyclonal antibody PA5-20389.
The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis.
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蛋白别名: TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1; TBC1 domain family member 1
基因别名: KIAA1108; TBC; TBC1; TBC1D1
UniProt ID: (Human) Q86TI0
Entrez Gene ID: (Human) 23216