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Highest antigen sequence indentity to the following orthologs: Mouse (98%), Rat (98%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59743. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1; TBC1 domain family member 1
基因别名: KIAA1108; TBC; TBC1; TBC1D1
UniProt ID: (Human) Q86TI0
Entrez Gene ID: (Human) 23216