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PEP-219 is a 17 amino acid synthetic peptide corresponding to amino acid residues 136-152 from human TC10. The sequence of this peptide is (amino to carboxy terminus): D (136) P K T L A R L N D M K E K P I C (152).
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, catalog # PA1-1061. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
TC10 is a member of the RAS superfamily of small GTP-binding proteins (see HRAS, MIM 190020) involved in insulin-stimulated glucose uptake.
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