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产品信息
RP-108139
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
ETNEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEI
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67489. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
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生物信息学
蛋白别名: EloC; Elongin 15 kDa subunit; elongin C; Elongin-C; RNA polymerase II transcription factor SIII subunit C; SIII p15; transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C); Transcription elongation factor B polypeptide 1
基因别名: ELOC; SIII; TCEB1
UniProt ID: (Human) Q15369
Entrez Gene ID: (Human) 6921
