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Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111674. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HMG box transcription factor 3; TCF-3; Transcription factor 7-like 1; transcription factor 7-like 1 (T-cell specific, HMG-box)
基因别名: TCF-3; TCF3; TCF7L1
UniProt ID: (Human) Q9HCS4
Entrez Gene ID: (Human) 83439