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Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55558. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
TESK2 or testis-specific kinase 2 is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. The kinase domain of TESK2 is structurally similar to the kinase domain of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). TESK2 is predominantly expressed in testis and prostate and plays an important role in spermatogenesis. TESK2 phosphorylates cofilin specifically at Ser-3 and induces formation of actin stress fibers and focal adhesions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Dual specificity testis-specific protein kinase 2; Testicular protein kinase 2
基因别名: TESK2
UniProt ID: (Human) Q96S53
Entrez Gene ID: (Human) 10420