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产品信息
RP-102224
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
QRSRLSVMAQYLCNVRHIFTIPGQAFVPKPEVDVGVVHFTPLIQPKIEQPFKLVEKVVQNVFQFRRKYCHRGLRMLFPEAQRLESTGRLLELADIDPTLRPRQLSISHFKSLCDVYRKMCDEDPQL
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (87%), Rat (87%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56142. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Dimethyladenosine transferase 1, mitochondrial; h-mtTFB; h-mtTFB1; homolog of yeast mitochondrial transcription factor B; hTFB1M; Mitochondrial 12S rRNA dimethylase 1; mitochondrial dimethyladenosine transferase 1; Mitochondrial transcription factor B1; OTTHUMP00000017473; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1
基因别名: CGI-75; CGI75; mtTFB; mtTFB1; TFB1M
UniProt ID: (Human) Q8WVM0
Entrez Gene ID: (Human) 51106
