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PEP-291 is a 16 amino acid synthetic peptide whose sequence is derived from the human TGN46 protein. The sequence of this peptide is (amino to carboxy terminus): V (252)-V-P-E-Q-P-S-W-K-D-H-S-K-P-I-S (267)
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, TGN46, catalog # PA1-1069. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1. and ASPP2. are activators of p53.
仅用于科研。不用于诊断过程。未经明确授权不得转售。