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Highest antigen sequence indentity to the following orthologs: Mouse (99%), Rat (99%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63305. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
TIMM50 (Mitochondrial import inner membrane translocase subunit TIM50) is an enzyme that in humans is encoded by the TIMM50 gene. Tim50 is a subunit of the Tim23 translocase complex in the inner mitochondrial membrane. Mutations in TIMM50 can lead to epilepsy, severe intellectual disability, and 3-methylglutaconic aciduria. TIMM50 expression is increased in breast cancer cells and decreased in hypertrophic hearts.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: homolog of yeast Tim50; MGC102733; Mitochondrial import inner membrane translocase subunit TIM50; Tim50-like protein; translocase of inner mitochondrial membrane 50 homolog
基因别名: PRO1512; TIM50; TIM50L; TIMM50
UniProt ID: (Human) Q3ZCQ8
Entrez Gene ID: (Human) 92609