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Highest antigen sequence indentity to the following orthologs: Mouse (70%), Rat (70%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51394. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Strong TKTL1 protein expression has been correlated with a certain type of glucose metabolism (aerobic glycolysis; Warburg effect) and to cells which are affected by chronic complications of diabetic patients. In colon and urothelial carcinomas, expression at the protein level is correlated with invasiveness of tumors and poor patient survival.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: TK 2; Transketolase 2; transketolase-2; transketolase-like 1; Transketolase-like protein 1; Transketolase-related protein
基因别名: TKR; TKT2; TKTL1
UniProt ID: (Human) P51854
Entrez Gene ID: (Human) 8277