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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66768. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: B lymphocyte gene 1; enhancer of split groucho 4; Grg-4; Groucho-related protein 4; transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 4, homolog of Drosophila E(sp1); Transducin-like enhancer protein 4
基因别名: BCE-1; BCE1; E(spI); ESG; ESG4; Grg-4; GRG4; KIAA1261; TLE4
UniProt ID: (Human) Q04727
Entrez Gene ID: (Human) 7091