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产品信息
A30520
产品规格
种属
Human
Expression System
Insect cells
氨基酸序列
1-510
标签
GST-tag
分子量
81.8 kDa
分类
Recombinant
类型
Protein
偶联物
形式
Liquid
浓度
See Label
纯化类型
purified
保存液
50mM tris HCl, pH 7.5, with 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, 10mM glutathione, 150mM NaCl, 25% glycerol
内含物
no preservative
保存条件
-80° C, Avoid Freeze/Thaw Cycles
运输条件
Dry ice
产品详细信息
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
This TNK1 recombinant human protein (1-510) was expressed in insect cells.
TNK1 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the Z'-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service
Protein Form: Recombinant, Active, Catalytic
The gene accession number for TNK1 is NP_003976.2.
靶标信息
TNK1 tyrosine kinase, non-receptor 1 belongs to the tyrosine protein kinase family and as such is an important regulator of intracellular signal transduction pathways mediating cellular proliferation, survival, and development. TNK1 is highly expressed in fetal tissues and at lower levels in a few adult tissues. TNK1 may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. TNK1 plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD38 negative kinase 1; MGC46193; Non-receptor tyrosine-protein kinase TNK1; TNK1; tyrosine kinase, non-receptor 1; tyrosine kinase, non-receptor, 1
基因别名: TNK1
UniProt ID: (Human) Q13470
Entrez Gene ID: (Human) 8711
