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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibodies, PA5-65326, PA5-61870. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
TRAPPC5 (trafficking protein particle complex 5), also known as TRS31, is a 181 amino acid protein belonging to the TRAPP (transport protein particle) small subunits family and the BET3 subfamily. Encoded by a gene that maps to human chromosome 19p13.2, TRAPPC5 is part of the multisubunit TRAPP tethering complex, which acts as a GTP exchange factor. Evolutionarily conserved, TRAPPC5 plays a role in protein binding,vesicle-mediated transport and nucleotide exchange stimulation. TRAPPC5 also performs guanine nucleotide exchanger factor (GEF) functions both in vitro and in vivo. Localizing to the Golgi apparatus, TRAPPC5 is essential for endoplasmic reticulum (ER)-to-Golgi and intra-Golgi vesicle trafficking in yeast, as well as additional transport events in mammals, such as post-Golgi trafficking.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Trafficking protein particle complex subunit 5
基因别名: TRAPPC5; TRS31
UniProt ID: (Human) Q8IUR0
Entrez Gene ID: (Human) 126003