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Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57208. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2- thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: lung cancer associated lncRNA 3; mitochondrial 5-methylaminomethyl-2-thiouridylate-methyltransferase; Mitochondrial tRNA-specific 2-thiouridylase 1; MTO2 homolog
基因别名: LCAL3; MTO2; MTU1; TRMT; TRMT1; TRMU; TRNT1
UniProt ID: (Human) O75648
Entrez Gene ID: (Human) 55687