Search Thermo Fisher Scientific
Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59430. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
TSEN34 encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3-prime end processing factor. A mutation in this gene results in the neurological disorder pontocerebellar hypoplasia type 2. Multiple alternatively spliced variants, encoding the same protein, have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CTD-3093M3.1; HsSen34; leukocyte receptor cluster (LRC) member 5; Leukocyte receptor cluster member 5; tRNA-intron endonuclease Sen34; tRNA-splicing endonuclease subunit Sen34; TSEN34 tRNA splicing endonuclease subunit
基因别名: LENG5; PCH2C; SEN34; SEN34L; TSEN34
UniProt ID: (Human) Q9BSV6
Entrez Gene ID: (Human) 79042