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Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83790. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
A novel putative serine/threonine kinase substrate gene (TSKS, for testis-specific kinase substrate) is likely the human homolog of the mouse testis-specific serine kinase substrate gene. TSKS exhibits high levels of expression exclusively in human testicular tissue. The expression of TSKS is downregulated in cancerous testicular tissue, in comparison to adjacent normal tissue. These observations suggest a role of TSKS in testicular physiology, most probably in the process of spermatogenesis or spermiogenesis.
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蛋白别名: protein phosphatase 1, regulatory subunit 161; STK22 substrate 1; testis specific serine/threonine kinase substrate; Testis-specific kinase substrate; Testis-specific serine kinase substrate
基因别名: PPP1R161; STK22S1; TSKS; TSKS1; TSSKS
UniProt ID: (Human) Q9UJT2
Entrez Gene ID: (Human) 60385