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Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59467. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: EF-hand binding protein 1; EF-hand-binding protein 1; Thioredoxin domain-containing protein 11
基因别名: EFP1; TXNDC11
UniProt ID: (Human) Q6PKC3
Entrez Gene ID: (Human) 51061