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Highest antigen sequence indentity to the following orthologs: Mouse (45%), Rat (45%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibodies, PA5-53065, PA5-82496. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Wybutosine is a hypermodified guanosine found in phenylalanine tRNA. Wybutosine functions to stabilize codon-anticodon interactions during ribosome decoding and therefore supports the maintenance of the reading frame. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. The human genome contains two closely related genes that putatively function in wybutosine synthesis. The open reading frame of this locus is disrupted in some individuals. Thus, this locus appears to be an evolving pseudogene, but may still be functional in some members of the population. [provided by RefSeq, Apr 2014].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: long intergenic non-protein coding RNA 69; MGC87315; Radical S-adenosyl methionine and flavodoxin domain-containing protein 2; radical S-adenosyl methionine and flavodoxin domains 1; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B; tRNA wybutosine-synthesizing protein 1 homolog B; tRNA-yW synthesizing protein 1 homolog B (non-protein coding)
基因别名: LINC00069; NCRNA00069; RSAFD2; TYW1B
UniProt ID: (Human) Q6NUM6
Entrez Gene ID: (Human) 441250