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产品信息
LF-P0021
产品规格
Expression System
E. coli
分类
Recombinant
类型
Protein
偶联物
形式
Lyophilized
保存条件
-20°C
运输条件
Wet ice
产品详细信息
After reconstitution, store at -80ºC and avoid freeze and thaw cycles.
Reconstitute using 500 µL deionized water.
靶标信息
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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