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产品信息
RP-88176
产品规格
种属
Human
Expression System
HEK293 cells
氨基酸序列
Human ULBP2, amino acids Met1-Ser217 (Accession # Q9BZM5) with a C-terminal human IgG1 Fc region
标签
Fc-tag
分子量
58 kDa
分类
Recombinant
类型
Protein
纯度
>95% as determined by SDS-PAGE.
内毒素浓度
<1.0 EU/µg
偶联物
形式
Lyophilized
纯化类型
purified
保存液
PBS, pH 7.4, with 5% mannitol, 5% trehalose, 0.01% Tween 80
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
It is recommended that the protein be aliquoted for optimal storage.
It is recommended that sterile water (400 µL) be added to the vial to prepare a stock solution of 0.25 mg/mL.
Concentration is measured by UV.
靶标信息
ULBP2 encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ALCAN-alpha; N2DL-2; NKG2D ligand 2; Retinoic acid early transcript 1H; UL16-binding protein 2
基因别名: ALCAN-alpha; N2DL2; NKG2DL2; RAET1H; ULBP2; UNQ463/PRO791
UniProt ID: (Human) Q9BZM5
Entrez Gene ID: (Human) 80328
