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Highest antigen sequence indentity to the following orthologs: Mouse (46%), Rat (46%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53782. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
UPF3A is part of a multiprotein post-splicing mRNP complex involved in both mRNA nuclear export and mRNA surveillance. UPF3A is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hUpf3; Nonsense mRNA reducing factor 3A; Regulator of nonsense transcripts 3A; Up-frameshift suppressor 3 homolog A
基因别名: HUPF3A; RENT3A; UPF3; UPF3A
UniProt ID: (Human) Q9H1J1
Entrez Gene ID: (Human) 65110