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Highest antigen sequence indentity to the following orthologs: Mouse (64%), Rat (64%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57425. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Tight junction-associated protein that is involved in the survival of auditory hair cells and hearing. Maybe by modulating the barrier properties and mechanical stability of tight junctions. Has no peptidase activity (PubMed:14715245). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Inactive ubiquitin carboxyl-terminal hydrolase 53; Inactive ubiquitin-specific peptidase 53; ubiquitin specific protease 53; ubiquitin specific proteinase 53; USP53
基因别名: KIAA1350; USP53
UniProt ID: (Human) Q70EK8
Entrez Gene ID: (Human) 54532