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产品信息
RP-108662
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
EIEGFPSPPDFILMADCIYYEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEIEKKYFELLQLDFDFEKIPLEKHDEEYRSEDIHIIYIRKK
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-85003. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
C14orf138, also named as VCPKMT or METTL21D, is 229 amino acid protein, which belongs to the methyltransferase superfamily. C14orf138 localizes in the cytoplasm and interacts with ALKBH6. C14orf138 as a Protein-lysine N-methyltransferase that specifically trimethylates 'Lys-315' of VCP/p97; this modification may decrease VCP ATPase activity. C14orf138 exists as five isoforms. The calculated molecular weight of C14orf138 is 26 kDa, but we always detected a 46-50 kDa protein by western blot.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: methyltransferase like 21D; Methyltransferase-like protein 21D; Protein N-lysine methyltransferase METTL21D; valosin containing protein lysine (K) methyltransferase; Valosin-containing protein lysine methyltransferase; VCP lysine methyltransferase; VCP-KMT
基因别名: C14orf138; METTL21D; VCP-KMT; VCPKMT
UniProt ID: (Human) Q9H867
Entrez Gene ID: (Human) 79609
