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Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54138. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: S53; vacuolar assembly protein 41; vacuolar protein sorting 41 homolog; Vacuolar protein sorting-associated protein 41 homolog; VPS41 HOPS complex subunit
基因别名: HVPS41; hVps41p; HVSP41; VPS41
UniProt ID: (Human) P49754
Entrez Gene ID: (Human) 27072