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Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-81887. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Human vaccinia-related kinase 1 (VRK1) is a new kinase related to a poxvirus kinase, and more distantly to the casein kinase 1 family. VRK1 shows strong autophosphorylating activity in several Ser and Thr residues. VRK has also been found to be an upstream regulator of p53 that belongs to a new signaling pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC117401; MGC138280; Serine/threonine-protein kinase VRK1; vaccinia virus B1R-related kinase 1; Vaccinia-related kinase 1
基因别名: PCH1; PCH1A; VRK1
UniProt ID: (Human) Q99986
Entrez Gene ID: (Human) 7443