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产品信息
RP-91778
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
AGSVGLALCGQTLVVRGGSRFLATSIASSDDDSLFIYDCSAAEKKSQENKGEDAPLDQGSGAILASTFSNSGSYFALTDDSKRLILFRTKPWQCLSVRTVAR
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (76%), Rat (76%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53600. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
Required for 7-methylguanosine modification of tRNA. This protein is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD). which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes. including cell cycle progression. signal transduction. apoptosis. and gene regulation. This protein is excluded as a candidate for a form of nonsyndromic deafness (DFNB10). but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternative splicing of this gene generates at least 3 transcript variants. two of which diverge at the 3' UTR and thus encode the same protein products.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hWH; Protein Wuho homolog; TRM82 tRNA methyltransferase 82 homolog; tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; tRNA (guanine-N(7)-)-methyltransferase subunit WDR4; WD repeat-containing protein 4; WDR4
基因别名: TRM82; TRMT82; WDR4
UniProt ID: (Human) B4DNQ7
Entrez Gene ID: (Human) 10785
