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Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59052. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
SKI8 is a component of the PAF and SKI complex which is composed of SKI2, SKI3 and SKI8. These are involved in transcriptional regulation and events downstream of RNA synthesis. Interaction of the SKI complex with SKI7 links the SKI complex to the exosome in order to perform mRNA degradation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Meiotic recombination REC14 protein homolog; recombination protein REC14; Ski8; SKI8 homolog; Superkiller complex protein 8; WD repeat-containing protein 61
基因别名: REC14; SKI8; SKIC8; WDR61
UniProt ID: (Human) Q9GZS3
Entrez Gene ID: (Human) 80349