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Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60582. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a member of the WW-and-C2-domain-containing family of proteins. Members of this family have two N-terminal WW domains that mediate binding to target proteins harboring L/PPxY motifs, an internal C2 domain for membrane association, and C-terminal alpha protein kinase C binding sites and class III PDZ domain-interaction motifs. Proteins of this family are able to form homo- and heterodimers and to modulate hippo pathway signaling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BH-3-only member B; BH3-only member B protein; Protein WWC2; WW domain-containing protein 2; WW, C2 and coiled-coil domain containing 2
基因别名: BOMB; WWC2
UniProt ID: (Human) Q6AWC2
Entrez Gene ID: (Human) 80014