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This peptide corresponds to 17 amino acid peptide near the carboxy terminus of human ZBTB3.
PEP-1197 can be used as a blocking peptide with polyclonal antibody PA5-21083.
The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. While little is known about ZBTB3, the related protein ZBTB2 is thought to be phosphorylated in response to the DNA damage, probably by either ATM or ATR. Other ZBTB proteins, such as ZBTB4 and ZBTB38 bind methylated DNA and repress transcription, suggesting that ZBTB3 may also act as a transcription repressor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
Entrez Gene ID: (Human) 79842