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产品信息
PEP-1202
产品规格
种属反应
Human
分类
Synthetic
类型
Peptide
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
purified
保存液
PBS, pH 7.2, with 0.1% BSA
内含物
0.02% sodium azide
保存条件
-20°C
产品详细信息
This peptide corresponds to 17 amino acids near the carboxy terminus of human ZBTB8.
PEP-1202 can be used as a blocking peptide with polyclonal antibody PA5-21088.
靶标信息
The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB8, also known as BOZ-F1, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB8, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB8 may act as a transcriptional repressor or be involved in tumorigenesis.
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生物信息学
蛋白别名: BOZ-F1; BTB/POZ and zinc-finger domain-containing factor; BTB/POZ and zinc-finger domains factor on chromosome 1; zinc finger and BTB domain containing 8; Zinc finger and BTB domain-containing protein 8A
基因别名: BOZF1; ZBTB8; ZBTB8A; ZNF916A
UniProt ID: (Human) Q96BR9
Entrez Gene ID: (Human) 653121
