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Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58557. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
ZC3H12C, also known as MCPIP3, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. Similar to ZC3H12A, ZC3H12C expression in macrophages is highly increased after treatment with lipopolysaccharide (LPS), suggesting it also may play a role in host immunity and inflammatory response.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MCP induced protein 3; MCP-induced protein 3; Probable ribonuclease ZC3H12C; Zinc finger CCCH domain-containing protein 12C
基因别名: KIAA1726; MCPIP3; ZC3H12C
UniProt ID: (Human) Q9C0D7
Entrez Gene ID: (Human) 85463