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产品信息
PHC1624
应用
建议稀释比
已发表文章
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
Human beta-Defensin 1 recombinant protein contains 36 amino acids
分子量
3.9 kDa
分类
Recombinant
类型
Protein
纯度
≥98% by SDS-PAGE and HPLC
内毒素浓度
<0.1 ng/µg
活性
ED50 = 100 - 1000 ng/mL; determined by the dose-dependent chemotaxis of of human CD34+ dendritic cells.
偶联物
形式
Lyophilized
纯化类型
purified
保存液
10mM acetic acid
内含物
no preservative
保存条件
-20°C
运输条件
Wet ice (domestic); Wet or Dry ice (international)
产品详细信息
Carrier-Free
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in aqueous buffers supplemented with carrier protein, such as 0.1-1.0% BSA.
Storage: This lyophilized preparation is stable at 2°C to 8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2°C to 8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C. Avoid repeated freeze/thaw cycles.
靶标信息
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.
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生物信息学
蛋白别名: BD-1; beta defensin 1; Beta-defensin 1; beta-defensin-1; Defensin, beta 1
基因别名: BD1; DEFB-1; DEFB1; DEFB101; HBD1
UniProt ID: (Human) P60022
Entrez Gene ID: (Human) 1672
