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产品信息
RP-88234
产品规格
种属
Mouse
Expression System
HEK293 cells
氨基酸序列
Mouse EPHA4, amino acids Met1-Thr547 (Accession # NP_031962.2) with a C-terminal His-tag
标签
His-tag
分子量
65 kDa
分类
Recombinant
类型
Protein
纯度
>98% as determined by SDS-PAGE.
内毒素浓度
<1.0 EU/µg
活性
Measured by its binding ability in a functional ELISA. Immobilized mouse EPHA4 at 2 µg/ml (100 µL/well) can bind mouse EFNA5 with a linear range of 1.28-32 ng/mL.
偶联物
形式
Lyophilized
纯化类型
purified
保存液
PBS, pH 7.4, with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
It is recommended that the protein be aliquoted for optimal storage.
It is recommended that sterile water (800 µL) be added to the vial to prepare a stock solution of 0.25 mg/mL.
Concentration is measured by UV.
靶标信息
EPHA4 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EphA4 encodes a protein that binds ephrin-A ligands.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: epa4; Ephrin type-A receptor 4; Tyrosine-protein kinase receptor MPK-3; Tyrosine-protein kinase receptor SEK-1
基因别名: 2900005C20Rik; AI385584; Cek8; Epha4; Hek8; rb; Sek; Sek1; Tyro1
UniProt ID: (Mouse) Q03137
Entrez Gene ID: (Mouse) 13838
