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产品信息
210-17E-25UG
产品规格
种属
Mouse
已发表种属
Mouse
Expression System
E. coli
氨基酸序列
MLRIQEGCSH LPSCCPSKEQ EPPEEWLKWS SASVSPPEPL SHTHHAESCR ASKDGPLNSR AISPWSYELD RDLNRVPQDL YHARCLCPHC VSLQTGSHMD PLGNSVPLYH NQTVFYRRPC HGEEGTHRRY CLERRLYRVS LACVCVRPRV MA
分子量
35 kDa
分类
Recombinant
类型
Protein
纯度
≥ 98% by SDS-PAGE gel and HPLC analyses.
内毒素浓度
<1 EU/µg
活性
Measured by its ability to induce GROalpha (CXCL1) secretion in HT-29 human colon adenocarcinoma cells.
偶联物
形式
Lyophilized
纯化类型
purified
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
产品详细信息
Recombinant Murine IL-17E is a 35.0 kDa disulfide-linked homodimer of two 152-amino-acid polypeptide chains.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
靶标信息
Interleukin 25 (IL-25) is a member of the IL-17 family and is identified as a proinflammatory cytokine which is produced by Th17 effector cells thus enabling the Th17 subset to initiate or maintain the autoimmune process in diseases such as Rheumatoid Arthritis. IL-25 also induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. IL-25 itself is activated through IL-23, IL-5, and TGF-beta.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: il 17e; IL-17E; IL-25; ILN; Interleukin; interleukin 17E; Interleukin-17E; Interleukin-25
基因别名: IL-17e; Il17e; Il25
UniProt ID: (Mouse) Q8VHH8
Entrez Gene ID: (Mouse) 140806
