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产品信息
PMC0184
应用
建议稀释比
已发表文章
产品规格
种属
Mouse
Expression System
E. coli
氨基酸序列
Mouse IL-18, amino acids 36-192 of the mature sequence
分子量
18 kDa
分类
Recombinant
类型
Protein
纯度
>90% by SDS-PAGE
内毒素浓度
<0.1 ng/µg
活性
Determined by the dose-dependent induction of IFN-gamma production in mouse IL-18 receptor transfected KG-1 cells.
偶联物
形式
Lyophilized
纯化类型
purified
保存液
PBS with 0.1% BSA, 1% sucrose
内含物
no preservative
保存条件
-20°C
运输条件
Wet ice (domestic); Wet or Dry ice (international)
产品详细信息
Reconstitution: We recommend that the vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the contents of the vial with 250 µL ice cold, sterile, distilled water on ice.
Storage: Store this lyophilized preparation at -20°C, preferably desiccated. Upon reconstitution, the protein may be stored at 2°C to 8°C for up to one week. For long term storage of the reconstituted protein, apportion into working aliquots and store at -80°C. Avoid repeated freeze/thaw cycles.
靶标信息
The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein can specifically interact with this cytokine, and thus negatively regulate its biological activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: IFN-gamma-inducing factor; il 18; IL-1 gamma; IL-18; ILN; Interferon gamma-inducing factor; interferon-gamma-inducing factor; Interleukin; Interleukin-1 gamma; Interleukin-18; Interleukin18; MGC12320
基因别名: Igif; Il-18; Il18
UniProt ID: (Mouse) P70380
Entrez Gene ID: (Mouse) 16173
