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产品信息
RP-88241
产品规格
种属
Mouse
Expression System
HEK293 cells
氨基酸序列
Mouse KLK1, amino acids Met1-Asp261 (Accession # P15947) with a C-terminal His-tag
标签
His-tag
分子量
36 kDa
分类
Recombinant
类型
Protein
纯度
>90% as determined by SDS-PAGE.
内毒素浓度
<1.0 EU/µg
活性
Measured by its ability to cleave a flourogenic peptide substrate Pro-Phe-Arg-7-amido-4-methylcoumarin (PFR-AMC). The specific activity is >6, 000 pmol/min/ µg. (Activation description: The proenzyme needs to be activated by Thermolysin for an activated form)
偶联物
形式
Lyophilized
纯化类型
purified
保存液
25mM tris, pH 7.4, with 5mM CaCl2, 0.01% mannitol, 0.15M NaCl, 5-8% trehalose, 0.01% Tween 80
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
It is recommended that the protein be aliquoted for optimal storage.
It is recommended that sterile water (200 µL) be added to the vial to prepare a stock solution of 0.25 mg/mL.
Concentration is measured by UV.
靶标信息
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 7S nerve growth factor gamma chain; 7S nerve growth factor gamma subunit; Gamma-NGF; Glandular kallikrein K1; Glandular kallikrein K3; KAL-B; Kallikrein 1-related peptidase b3; kallikrein 6; kallikrein renal/pancreas/salivary; Kallikrein-1; mGK-3; mGK-6; nerve growth factor, gamma; Renal kallikrein; Tissue kallikrein-3; Tissue kallikrein-6; true tissue kallikrein
基因别名: 0610007D04Rik; Kal; Klk-3; Klk-6; Klk1; Klk1b3; Klk1b6; Klk3; Klk6; mGk-3; mGk-6; Ngfg
UniProt ID: (Mouse) P15947, (Mouse) P00756
Entrez Gene ID: (Mouse) 16612, (Mouse) 18050
