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产品信息
RP-88242
产品规格
种属
Mouse
Expression System
HEK293 cells
氨基酸序列
Mouse KLK11 isoform 2, amino acids Met1-Asn276 (Accession # Q9QYN3) with a C-terminal His-tag
标签
His-tag
分子量
38-42 kDa
分类
Recombinant
类型
Protein
纯度
>95% as determined by SDS-PAGE.
内毒素浓度
<1.0 EU/µg
偶联物
形式
Lyophilized
纯化类型
purified
保存液
PBS, pH 7.4, with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
It is recommended that the protein be aliquoted for optimal storage.
It is recommended that sterile water (80 µL) be added to the vial to prepare a stock solution of 0.25 mg/mL.
Concentration is measured by UV.
靶标信息
Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of KLK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Hippostasin; kallikrein 11; Kallikrein-11; Kallikrein11; protease, serine, 20; Serine protease 20
基因别名: 2310015I08Rik; Klk11; Prss20; TLSP
UniProt ID: (Mouse) Q9QYN3
Entrez Gene ID: (Mouse) 56538
