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产品信息
PEP-164
产品规格
分类
Synthetic
类型
Peptide
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
PEP-164 is an 18 amino acid synthetic peptide whose sequences are derived from mouse PC1 protein. The sequence of this peptide is (amino to carboxy terminus): S (111)-V-Q-K-D-S-A-L-D-L-F-N-D-P-M-W-N (127)
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and mouse PC1, catalog # PA1-057. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
靶标信息
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. The use of alternate polyadenylation sites has been found for this gene. Multiple alternatively spliced transcript variants have been described for this gene but their full length nature is not known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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