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PEP-287 is a 19 amino acid synthetic peptide whose sequence is derived from the rat CSP protein. The sequence of this peptide is (amino to carboxy terminus): E (180)-T-T-Q-L-T-A-D-S-H-P-S-Y-H-T-D-G-F-N (198)
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, Cysteine String Protein Alpha, catalog # PA1-776. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
Cysteine string protein alpha (CSPalpha)/DNAJC5 is a synaptic vesicle protein that contains a DNA-J domain characteristic of Hsp40 chaperones. Cysteine-string proteins are membrane-bound proteins associated primarily with nerve endings and synaptic vesicles in the brain. These proteins play an important role in presynaptic function and may be involved in calcium-dependent neurotransmitter release. CSP proteins may act as presynaptic chaperones that assist in maintaining synaptic function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CSP; CSP-beta; Cysteine string protein; Cysteine string protein beta; DnaJ homolog subfamily C member 5; DnaJ homolog subfamily C member 5B
基因别名: Csp; Dnajc5; Dnajc5b; RGD1562486
UniProt ID: (Rat) P60905, (Rat) D3ZD82
Entrez Gene ID: (Rat) 79130, (Rat) 499579