Antibodies that detect CD47 can be used in several scientific applications, including Flow Cytometry, Immunohistochemistry, Western Blot, Immunocytochemistry and SDS-PAGE. These antibodies target CD47 in Human, Mouse, Rat, Non-human primate and Porcine samples. Our CD47 monoclonal,...Antibodies that detect CD47 can be used in several scientific applications, including Flow Cytometry, Immunohistochemistry, Western Blot, Immunocytochemistry and SDS-PAGE. These antibodies target CD47 in Human, Mouse, Rat, Non-human primate and Porcine samples. Our CD47 monoclonal, polyclonal and recombinant monoclonal...Antibodies that detect CD47 can be used in several scientific applications, including Flow Cytometry, Immunohistochemistry, Western Blot, Immunocytochemistry and SDS-PAGE. These antibodies target CD47 in Human, Mouse, Rat, Non-human primate and Porcine samples. Our CD47 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit, Rat and Goat. These antibodies have been verified by Cell treatment to confirm specificity to CD47. Find the CD47 antibody that fits your needs. Choose from 1 of 140 CD47 antibodies, which have been validated in experiments with 226 publications and 472 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other...
Antibodies that detect CD47 can be used in several scientific applications, including Flow Cytometry, Immunohistochemistry, Western Blot, Immunocytochemistry and SDS-PAGE. These antibodies target CD47 in Human, Mouse, Rat, Non-human primate and Porcine samples. Our CD47 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit, Rat and Goat. These antibodies have been verified by Cell treatment to confirm specificity to CD47. Find the CD47 antibody that fits your needs. Choose from 1 of 140 CD47 antibodies, which have been validated in experiments with 226 publications and 472 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
CD47 (integrin-associated protein, IAP) is a ubiquitously expressed cell surface transmembrane glycoprotein interacting with several integrins and regulating their functions. Engagement of CD47 by soluble ligands or counter receptors modulates various signaling pathways, such as activation of heterotrimeric G proteins. Functionally, CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. CD47 is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. CD47 has broad tissue distribution, is reduced in expression on Rh erythrocytes. CD47 acts as a ligand for CD172a (signal regulatory protein alpha, SIRP alpha), an immune inhibitory receptor on macrophages; this interaction prevents phagocytosis of CD47-positive cells. Moreover, CD47-CD172a system affects cell migration, B cell adhesion, T cell activation, and is involved in modulation of chondrocyte responses to mechanical signals, and promotes neuronal development, being especially abundant in synapse-rich regions of brain and retina.
同义词
9130415E20Rik; AA407862; AI848868; antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; AW108519; B430305P08Rik; Cd47; CD47 antigen; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 antigen/integrin-associated protein; CD47 glycoprotein; Cd47 molecule; CD47/IAP; IAP; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; Itgp; Leukocyte surface antigen CD47; MER6; OA3; Protein MER6; Rh-related antigen; sCD47; soluble CD 47; soluble CD47
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