Antibodies that detect Desmoglein 3 can be used in several scientific applications, including Immunohistochemistry, Western Blot, SDS-PAGE, Peptide array and Immunocytochemistry. These antibodies target Desmoglein 3 in Human, Mouse and Rat samples. Our Desmoglein 3 monoclonal,...Antibodies that detect Desmoglein 3 can be used in several scientific applications, including Immunohistochemistry, Western Blot, SDS-PAGE, Peptide array and Immunocytochemistry. These antibodies target Desmoglein 3 in Human, Mouse and Rat samples. Our Desmoglein 3 monoclonal, polyclonal and recombinant monoclonal antibodies are...Antibodies that detect Desmoglein 3 can be used in several scientific applications, including Immunohistochemistry, Western Blot, SDS-PAGE, Peptide array and Immunocytochemistry. These antibodies target Desmoglein 3 in Human, Mouse and Rat samples. Our Desmoglein 3 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. These antibodies have been verified by Relative expression to confirm specificity to Desmoglein 3. Find the Desmoglein 3 antibody that fits your needs. Choose from 1 of 30 Desmoglein 3 antibodies, which have been validated in experiments with 81 publications and 111 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other...
Antibodies that detect Desmoglein 3 can be used in several scientific applications, including Immunohistochemistry, Western Blot, SDS-PAGE, Peptide array and Immunocytochemistry. These antibodies target Desmoglein 3 in Human, Mouse and Rat samples. Our Desmoglein 3 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. These antibodies have been verified by Relative expression to confirm specificity to Desmoglein 3. Find the Desmoglein 3 antibody that fits your needs. Choose from 1 of 30 Desmoglein 3 antibodies, which have been validated in experiments with 81 publications and 111 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
Desmoglein 3 (Dsg3), also known as Cadherin family member 6 (CDHF6), is a member of the desmosomal cadherin family and plays a critical role in cell-cell adhesion. It is predominately expressed in stratified squamous epithelium, including the skin, oral mucosa, and esophagus. Desmoglein 3 has been characterized as the auto-antigen of pemphigus vulgaris (PV), a life-threatening autoimmune disease. Binding of anti-Desmoglein 3 autoantibodies causes the loss of cell-cell adhesion, which clinically manifests as blisters on the skin and oral mucosa, and histologically as suprabasilar acantholysis.
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