Antibodies that detect JAK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target JAK1 in Human, Mouse, Rat and Non-human primate samples. Our JAK1 polyclonal and recombinant...Antibodies that detect JAK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target JAK1 in Human, Mouse, Rat and Non-human primate samples. Our JAK1 polyclonal and recombinant monoclonal antibodies are developed...Antibodies that detect JAK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target JAK1 in Human, Mouse, Rat and Non-human primate samples. Our JAK1 polyclonal and recombinant monoclonal antibodies are developed in Rabbit. These antibodies have been verified by Cell treatment to confirm specificity to JAK1. Find the JAK1 antibody that fits your needs. Choose from 1 of 22 JAK1 antibodies, which have been validated in experiments with 31 publications and 64 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data...
Antibodies that detect JAK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target JAK1 in Human, Mouse, Rat and Non-human primate samples. Our JAK1 polyclonal and recombinant monoclonal antibodies are developed in Rabbit. These antibodies have been verified by Cell treatment to confirm specificity to JAK1. Find the JAK1 antibody that fits your needs. Choose from 1 of 22 JAK1 antibodies, which have been validated in experiments with 31 publications and 64 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
Janus kinase 1 (JAK1), is a protein tyrosine kinase that is involved in the interferon-alpha/beta and -gamma signal transduction pathways. Immunological stimuli, such as interferons and cytokines, induce recruitment of Stat transcription factors to cytokine receptor-associated JAK1. JAK1 then phosphorylates proximal Stat factors, which subsequently dimerize, translocate to the nucleus and bind to cis elements upstream of target gene promoters to regulate transcription. Upon ligand binding, JAK1 undergoes tyrosine phosphorylation and catalytic activation in an interdependent manner. Phosphorylation of tyrosine residues at positions 1022 and 1023 is believed to function in the activation of catalytic events.
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